It really is concluded that EAM-2201 has the potential to bring about in vivo pharmacokinetic drug interactions when co-administered with substrates of CYP2C8, CYP3A4 and UGT1A3, and it is evaluated in pooled human liver microsomes. EAM-2201 was incubated with human hepatocytes for three h inside of a CO2 incubator and also the metabolites of E